Protandim Nrf2 and NRF1 Synergizers work together to reduce oxidative stress and support mitochondria biogenesis and function. With the addition of NAD Synergizer, we can now target other biochemical pathways known to support healthy aging and increased health span.

Researchers and scientists agree that aging is the natural result of overall cellular deterioration. One major way this occurs is through exposure to free radicals, other oxidants, and toxicological insults. It is impossible to avoid these exposures because the food you eat, the air you breathe, our modern lifestyles, stress, and even exercise, but we can do certain things to maintain our health as we age. The human body naturally fights these insults by producing its own antioxidant and detoxification enzymes through Nrf2-dependent mechanisms. However, as we grow older, Nrf2 works less efficiently. That’s where Protandim® Nrf2 Synergizer TM plays a critical role. It supports these Nrf2-dependent mechanisms to boost the body’s production of antioxidant and detoxification enzymes. Another natural phenomenon relating to the aging process is our mitochondria (the cell’s powerplant) begins working less efficiently. Less efficient mitochondria produce less energy and produce excess free radicals and other oxidants. Supporting overall mitochondrial function is important to promote overall health as we age. Protandim NRF1 was designed to both increase mitochondrial number and provide ingredients shown to support mitochondrial health. Lastly, another major significant effect of the aging process is a decline of cellular NAD levels and reduction of sirtuin activity. Sirtuin activity has been shown to play a major roll in supporting overall health. Protandim® NAD Synergizer TM was designed to support NAD levels and sirtuin activity. Thus, taking the entire Protandim family of products will help support all of these significant aspects of the aging process.*

Protandim Nrf2 Synergizer is the only supplement proven in a peerreviewed, human clinical study to reduce cellular stress in humans by an average of 40 percent in 30 days. Protandim Nrf2 Synergizer is patent protected and is the subject of 20 peer-reviewed clinical studies. Protandim Nrf2 Synergizer works to support the body’s own protective measures by turning on its internal antioxidant defense system, regulated by the protein Nrf2. When activated, Nrf2 triggers cells to produce naturally occurring antioxidant enzymes as well as housekeeping “cleanup” proteins which work together to deliver balanced protection against cellular stress.

• Withania somnifera (Ashwagandha) root extract (sourced from India)
• Camellia sinensis (Green Tea) leaf extract (sourced from China)
• Silybum marianum (Milk Thistle) seed extract (sourced from China)
• Bacopa monnieri (Bacopa) whole plant extract (sourced from India)
• Curcuma longa (Turmeric) root extract (sourced from India)

No, the individual ingredients in Protandim Nrf2 Synergizer aren’t as effective in activating the Nrf2 pathway as LifeVantage’s botanical blend. Previous studies of Protandim Nrf2 Synergizer have shown a very clear and potent synergy whereby the 5-ingredient blend is significantly more effective than any of the individual ingredients in
1) inducing Nrf2;
2) triggering the production of internal antioxidant enzymes and;
3) stimulating the expression of a variety of cellular survival genes.